Microfluidics – Organ-on-chip

The Role of Microfluidics for Organ on Chip Simulations

A multichannel three-dimensional chip of a microfluidic cell culture which enables the simulation of organs is called an "organ on a chip" (OC). With the integration of many other technologies, OCs have been mimicking organs, substituting animal models, and diminishing the time and cost of experiments which is better than the preceding conventional in vitro models, which make them imperative to...

Microfluidics Toward a Lab-on-a-Chip

H.A. Stone,1 A.D. Stroock,2 and A. Ajdari3 1Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138; email: [email protected] 2School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853; email: [email protected] 3Physico-Chimie Théorique, UMR CNRS-ESPCI 7083, ESPCI, 10 rue Vauquelin, 75005 Paris, France; email: armand@...

Optical sensing for on-chip digital microfluidics

A digital microfluidic architecture is introduced for micron-scale localized fluid actuation and in in-situ optical sensing. Contemporary device integration challenges related to localization and device scalability are overcome through the introduction of a bi-layered digital microfluidic multiplexer. Trinary inputs are applied through differential combinations of voltage signals between upper ...

Microfluidics for miniaturized laboratories on a chip.

Microfluidic systems promise solutions for high throughput and highly specific analysis for biology, medicine and chemistry while consuming only tiny amounts of reactants and space. On these lab-on-a-chip platforms often multiple physical effects such as electrokinetic, acoustic or capillary phenomena from various disciplines are exploited to gain the optimal functionality. The fluidics on thes...

Portable High Throughput Digital Microfluidics and On-Chip Bacteria Cultures